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05
Jun
2011
NIH Pituitary Clinical Trials Updated 6/5/2011
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Rank

Status Study
1 Recruiting Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary Adenoma
Condition: Pituitary Tumor
Intervention:
2 Not yet recruiting Evaluate the Efficacy and Safety of Pasireotide LAR on the Treatment of Patients With Clinically Non-Functioning Pituitary Adenoma
Condition: Nonfunctioning Pituitary Tumor
Intervention: Drug: Pasireotide LAR
3 Recruiting Pituitary Tumor Surveillance: Pathogenic Correlation
Condition: Pituitary Tumor
Intervention:
4 Unknown  Measurement of Pituitary Volume and Hormonal Changes in Patients With Post-Traumatic Stress Disorder
Condition: Posttraumatic Stress Disorder
Interventions: Procedure: MRI of the pituitary;   Procedure: DEX/CRH test
5 Recruiting Temozolomide in Treating Patients With Invasive Pituitary Tumors
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: temozolomide;   Genetic: DNA methylation analysis;   Genetic: microarray analysis;   Genetic: protein expression analysis;   Genetic: proteomic profiling;   Other: laboratory biomarker analysis
6 Recruiting An Investigation of Pituitary Tumors and Related Hypothalmic Disorders
Conditions: Abnormalities;   Craniopharyngioma;   Cushing's Syndrome;   Endocrine Disease;   Pituitary Neoplasm
Intervention:
7 Recruiting Study of Thyrotropin-Releasing Hormone in Normal Volunteers and in Patients With Thyroid or Pituitary Abnormalities
Conditions: Healthy;   Pituitary Disease;   Thyroid Disease
Intervention: Drug: TRH (Thyrotropin Releasing Hormone)
8 Recruiting The Diagnostic Accuracy of the Glucagon Stimulation Test for Evaluation of Adult Growth Hormone Deficiency and the Hypothalamic-Pituitary-Adrenal Axis
Conditions: Adult Growth Hormone Deficiency;   Hypothalamic-pituitary Disorders
Interventions: Procedure: Glucagon stimulation test and insulin tolerance test;   Procedure: glucagon stimulation test and insulin tolerance test
9 Recruiting Proton Radiation Therapy for Pituitary Adenoma
Condition: Pituitary Adenoma
Intervention: Radiation: Proton Radiation Therapy
10 Recruiting Ante-hypophyseal Dysfunctions in Children Following Moderate to Severe Traumatic Brain Injuries
Condition: Moderate to Severe Traumatic Brain Injury
Intervention: Other: Biological and behavioral explorations
11 Recruiting Targeted Therapy With Lapatinib in Patients With Recurrent Pituitary Tumors Resistant to Standard Therapy
Conditions: Adenoma;   Prolactinoma
Intervention: Drug: Lapatinib
12 Not yet recruiting To Describe the Effect of rhLH Supplementation in Women With Hyporesponse to rhFSH After Pituitary Downregulation
Condition: Infertility
Intervention: Drug: Luveris
13 Recruiting The Effect of Monoclonal Vascular Endothelial Growth Factor (VEGF) Antibody (Bevacizumab) on Pituitary Function
Conditions: Colorectal Cancer;   Lung Cancer;   Breast Cancer;   Glioblastoma
Intervention:
14 Recruiting Anterior Pituitary Hormone Replacement in Traumatic Brain Injury
Conditions: Growth Hormone Deficiency;   Traumatic Brain Injury
Interventions: Drug: Human Growth Hormone;   Drug: Placebo
15 Recruiting Rosiglitazone in Treating Patients With Newly Diagnosed ACTH-Secreting Pituitary Tumor (Cushing Disease)
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: rosiglitazone maleate;   Other: laboratory biomarker analysis
16 Recruiting Evaluation of Patients With Thyroid Disorders
Conditions: Hyperthyroidism;   Hypothyroidism;   Pituitary Neoplasm
Intervention:
17 Recruiting Effects of Growth Hormone Administration on Cardiovascular Risk in Cured Acromegalics With Growth Hormone Deficiency
Conditions: Acromegaly;   Growth Hormone Deficiency;   Pituitary Disease
Interventions: Drug: Somatropin;   Drug: Placebo
18 Unknown  Pituitary Functions After Traumatic Brain Injury (TBI) and/or Subarachnoid Hemorrhage (SAH)
Conditions: Traumatic Brain Injury;   Subarachnoid Hemorrhage;   Hypopituitarism
Intervention:
19 Recruiting The Treatment and Natural History of Acromegaly
Conditions: Acromegaly;   Pituitary Neoplasm
Intervention:
20 Recruiting Barrow Nasal Inventory Survey
Condition: Pituitary Tumors
Intervention:

 

Rank Status Study
21 Recruiting VRS-317 in Adult Subjects With Growth Hormone Deficiency
Condition: Growth Hormone Deficiency
Intervention: Drug: VRS-317
22 Recruiting Age-related Variability of the Efficacy and Tolerability of Alternative Pituitary Suppression Regimens in ART
Condition: Infertility
Intervention: Drug: hFSH(Fostimon)
23 Unknown  Does Topical Steroid Treatment Impair the Adrenal Function?
Conditions: Hypothalamus-Pituitary-Adrenal Axis Assessement;   Topical Steroid Therapy in Chronic Skin Diseases
Intervention:
24 Recruiting Assessment of Pituitary Adenylate Cyclase Activating Polypeptide-Brain Derived Neurotrophic Factor (PACAP-BDNF) Signaling System Involvement in Etiology and Treatment of Major Depression
Condition: Major Depression
Intervention: Drug: SSRI; SNRI; TCA
25 Recruiting Study of Pasireotide in Patients With Rare Tumors of Neuroendocrine Origin
Conditions: Pancreatic Neoplasm;   Pituitary Neoplasm;   Nelson Syndrome;   Ectopic ACTH Syndrome
Intervention: Drug: Pasireotide LAR
26 Unknown  Pituitary Derived-Intermedin is an Estrogen-Modulated Factor for Reducing Blood Pressure
Conditions: Menopause;   Hypertension
Intervention: Behavioral: intermedin
27 Recruiting Adult Growth Hormone Deficiency and Cardiovascular Risk
Condition: Growth Hormone Deficiency
Interventions: Procedure: Blood draws;   Drug: Growth hormone releasing hormone (GHRH) and arginine;   Procedure: Carotid ultrasound;   Procedure: MRI;   Procedure: Endothelial cell biopsy
28 Recruiting Quetiapine Prolong, Escitalopram and Hypothalamic-pituitary-adrenocortical (HPA) Axis Activity in Depressed Patients
Condition: Major Depression
Interventions: Drug: quetiapine;   Drug: escitalopram
29 Recruiting Stress, Hypothalamic-Pituitary-Adrenal (HPA) Dysfunction, and Relapse in Alcoholism
Condition: Alcohol Dependence
Intervention:
30 Recruiting A Comparative Study of Global 12 Lead Electroencephalogram to Frontal SedlineTM Electroencephalogram
Conditions: Craniotomy;   Transphenoidal Pituitary Resection
Intervention:
31 Recruiting Genetics of Endocrine Tumours
Condition: Acromegaly
Intervention:
32 Unknown  Testosterone Gel Applied to Women With Pituitary Gland Problems
Condition: Panhypopituitarism
Intervention: Drug: Transdermal Testosterone gel
33 Recruiting Lanreotide as Primary Treatment for Acromegalic Patients With Pituitary Gland Macroadenoma
Condition: Acromegaly
Intervention: Drug: Lanreotide autogel 120 mg
34 Recruiting Detection and Treatment of Endocrine Abnormalities in Childhood Cancer Survivors
Conditions: Hypopituitarism;   Hypogonadism;   Thyroid Dysfunction;   Bone Diseases, Metabolic
Intervention:
35 Recruiting A Study Examining the Peri- and Post-operative Dynamics of the Growth Hormone (GH) - IGF-1 Axis in Subjects With Acromegaly During the First Year After Surgical Resection
Condition: Acromegaly
Intervention: Other: OGTT
36 Recruiting Clinical and Biological Characteristics of Psychotic Depression
Conditions: Depression;   Psychotic Disorders;   Depressive Disorder, Major
Intervention:
37 Recruiting Efficacy and Safety of Pasireotide Long Acting Release (LAR) Versus Octreotide LAR or Lanreotide Autogel (ATG) in Patients With Inadequately Controlled Acromegaly
Condition: Acromegaly
Interventions: Drug: Pasireotide (SOM230);   Drug: octreotide LAR 30mg or lanreotide ATG 120mg
38 Recruiting Single Dose FSH-GEX™ in Healthy Volunteers
Condition: Female Infertility
Interventions: Drug: FSH-GEX™;   Drug: Comparator 1;   Drug: Comparator 2;   Drug: Placebo
39 Recruiting Endocrine and Psychological Evaluation of Adopted Children
Condition: Psychosocial Adjustment
Intervention:
40 Recruiting Safety and Efficacy of LCI699 in Cushing's Disease Patients
Condition: Cushing Disease
Intervention: Drug: LCI699
Last Updated ( Sunday, 05 June 2011 18:36 )
 
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